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KMID : 0984720070390060338
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Infection and Chemotherapy
2007 Volume.39 No. 6 p.338 ~ p.341
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Thrombosis in Patients with Acquired Immunodeficiency Syndrome
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Lee Jae-Hoon
Park Wan-Beom
Choe Kang-Won
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Abstract
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Patients with HIV infection may be at increased risk of thrombosis. A variety of mechanism have been proposed to account for hypercoagulability in HIV-infected patients. These include decreased plasma concentrations of protein S, opportunistic infection, tumor such as Kaposi’s sarcoma, drugs such as megestrol acetate, protease inhibitor, and presence of anticardiolipin antibody. The authors report three cases of thrombosis in AIDS patients. One case was renal vein thrombosis associated with abnormalities of protein S and anticardiolipin IgG. Two cases were pulmonary embolism associated with megestrol acetate.
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KEYWORD
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Thrombosis, Hypercoagulability, Megestrol a cetate, AIDS
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